Prof. Dr. Eric Beitz

Pharmaceutical und Medicinal Chemistry        portrait           
Christian-Albrechts-University of Kiel
Gutenbergstraße 76
24118 Kiel

Tel. +49 431 880 1809
Fax.  +49 431 880 1352

ebeitz@pharmazie.uni-kiel.de
 
Curriculum vitae

Secretary:
Larissa Einfeldt
Tel.  +49 431 880 1131
leinfeldt@pharmazie.uni-kiel.de

 

Latest Publications

Köpnick, A.L., Jansen, A., Geistlinger, K., Epalle, N.H., Beitz, E. (2021) Basigin drives intracellular accumulation of L-lactate by harvesting protons and substrate anions. PLoS One 16: e0249110. PubMed

Schmidt, J.D.R., Walloch, P., Höger, B., Beitz, E. (2021) Aquaporins with lactate/lactic acid permeability at physiological pH conditions. Biochimie (Epub ahead of print) PubMed

Walloch, P., Hansen, C., Priegann, T., Schade, D., Beitz, E. (2021) Pentafluoro-3-hydroxy-pent-2-en-1-ones potently inhibit FNT-type lactate transporters from all five human-pathogenic Plasmodium species. ChemMedChem 16: 1283-1289. PubMed

Current grants

- Anti-malarials targeting the plasmodial transketolase and the lactate transporter (TWAS-DFG programme)
- Structure elucidation of the inhibitor-bound plasmodial lactate transporter (DFG)
-
Proton transport and proton-coupled transport (EC, Horizon 2020, Marie Skłodowska-Curie Innovative Training Networks)  "PROTON" website

Main interests of the group

Transmembrane transport of water, solutes and metabolites | biophysics and transport mechanisms | molecular regulation, selectivity mechanisms, and inhibition of aquaporins and metabolite transporters from humans and pathogenic parasites | evaluation of drug targets  | inhibitor screening, design, and synthesis

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