Konferenzbeiträge (conference contributions)

Bock, S. and Scherließ, R., Particle engineering for Dry Powder Inhalation (DPI): Modifying drug-to-carrier interaction in adhesive mixtures, 1st annual Nordic POP meeting, Oslo, Norway (2019), oral presentation

Gutowski, T. and Scherließ, R., Cannabidiol in a DPI – maximising the spray drying yield of HPMC matrix particles Drug Delivery to the Lungs 2018, Edinburgh, UK (2018)

Etschmann, C. and Scherließ, R., Softpellets for high dose pulmonary delivery, Drug Delivery to the Lungs 2018, Edinburgh, UK (2018)

Rhein, N., Birk, G. and Scherließ, R., A closer look on the dispersion behaviour of Parteck® M DPI – based interactive mixtures: improving the fine particle fraction by the addition of fines, Drug Delivery to the Lungs 2018, Edinburgh, Scotland (2018)

Jüptner, A., Sarrailh, S. and Scherließ, R., Spray dried powders for nasal application - Influence of particle morphology and filling process on aerosol generation, Drug Delivery to the Lungs 2018, Edinburgh, Scotland (2018)

Hellfritzsch, M. and Scherließ, R., Characterisation of Zinc Oxide as an Alternative to Aluminum Hydroxide in Nasal Vaccination, Drug Delivery to the Lungs 2018, Edinburgh, Scotland (2018)

Scherließ, R., Reinauer, E. and Kemter, K., Stability of Dry Powder Vaccines, 12th Vaccine Congress, Budapest, Hungary (2018)

Tanabe, S., Gopireddy, S., Ando, S., Minami, H., Urbanetz, N.A. and Scherließ, R., Prediction of Blend Uniformity by utilizing Discrete Element Method simulation, AIChE Annual Meeting, Pittsburgh, USA (2018) selected for oral presentation

Hildebrandt, C., Gopireddy, S.R., Scherließ, R. and Urbanetz, N., Impact of force feeder geometry on powder flow, 11th World Meeting of Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain (2018)

Jüptner, A., Hellfritzsch, M., Kaj, C., Vimont, A., Sarrailh, S., Williams, G. and Scherließ, R., Spray dried formulations for inhalation - influence of particle shape, 11th World Meeting of Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain (2018)

Rhein, N., Birk, G. and Scherließ, R., Influence of carrier particle size distribution and inhaler devices on aerodynamic performance, 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain (2018)

Heidland, J. and Scherließ, R., Aerodynamic characterisation of nano-in-microparticulate formulation for dry powder vaccination, 11th World Meeting of Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain (2018) 396-399

Tanabe, S., Gopireddy, S., Ohno, I., Minami, H., Ando, S., Scherließ, R. and Urbanetz, N.A., Blend Uniformity Prediction based on Discrete Element Method (DEM) Simulation, World Meeting of Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain (2018)

Hellfritzsch, M. and Scherließ, R., Characterisation of Zinc Oxide Particles as Protein Carrier System, 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain (2018)

Gutowski, T. and Scherließ, R., Cannabidiol in a DPI – Preliminary experiments to screen formulation technologies and excipients, 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Granada, Spain (2018)

Saarinen, J., Gütter, F., Lindman, M., Fraser-Miller, S., Scherließ, R., Isomäki, A., Jokitalo, E., Santos, H.A., Peltonen, L. and Strachan, C., Synergistic Analysis of Nanoparticle Cellular Uptake Using Correlative Coherent Anti-Stokes Raman Scattering and Electron Microscopy, Finnish Physical Pharmacy Society meeting (2018)

Gütter, F., Saarinen, J., Peltonen, L., Santos, H., Strachan, C. and Scherließ, R., Understanding nano-bio interactions by characterisation of nanocrystal-cell relations, 22nd annual meeting CRS Germany local chapter, Halle (2018)

Winter, E., Lettau, M., Heidland, J., Scherließ, R., Walter, F., Helm, O. and Sebens, S., Tumor vaccination: chitosan nanoparticles to improve the antigen uptake by dendritic cells for an enhanced tumor-directed immune response, 5th European Congress of Immunology, Amsterdam, The Netherlands (2018)

Wöll, S., Gockel, L.M., Schiller, S. and Scherließ, R., Spray drying of Liposomes: Surface Stabilizer Relationship, CRS local chapter Germany annual meeting, Marburg (2017), oral presentation

Heidland, J. and Scherließ, R., Nano-in-microparticles for dry powder vaccination via the respiratory tract, CRS local chapter Germany annual meeting, Marburg (2017)

Rhein, N., Birk, G. and Scherließ, R., Parteck M DPI – a novel mannitol as carrier in dry powder inhalation formulations, 2nd European Conference on Pharmaceutics, Krakow, Poland (2017) 139-142

Hertel, M., Schwarz, E., Kobler, M., Hauptstein, S., Steckel, H. and Scherließ, R., How to determine the ideal amount of fines in dry powder inhaler formulations?, 9th Polish-German Symposium on Pharmaceutical Sciences, Krakow, Poland (2017)

Gütter, F., Peltonen, L., Strachan, C. and Scherließ, R., Nanocrystal production: Understanding stabiliser-drug interaction, 9th Polish-German Symposium on Pharmaceutical Sciences, Krakow, Poland (2017)

Rhein, N., Birk, G. and Scherließ, R., Storage stability of a novel mannitol carrier in a dry powder inhalation formulation 9th Polish-German Symposium on Pharmaceutical Sciences, Krakow, Poland (2017)

Saarinen, J., Gütter, F., Fraser, S., Isomäki, A., Antikainen, O., Scherließ, R., Jokitalo, E., Santos, H., Peltonen, L. and Strachan, C., Correlative light-electron microscopy (CLEM) of drug nano-/microcrystal cellular uptake with coherent anti-Stokes Raman scattering (CARS) CRS Nordic Chapter Meeting, Kuopio, Finland (2017)

Hildebrandt, C., Gopireddy, S., Scherließ, R. and Urbanetz, N.A., Numerical analysis of the die filling process within a pharmaceutical tableting machine, 8. Symposium Produktgestaltung in der Partikeltechnologie. Fraunhofer ICT, Karlsruhe (2017) oral presentation

Hildebrandt, C., Gopireddy, S., Scherließ, R. and Urbanetz, N.A., Powder flow within a pharmaceutical tablet press – a DEM analysis, V International Conference on Particle-Based Methods - Fundamentals and Applications PARTICLES2017, Hanover (2017) oral presentation

Hildebrandt, C., Gopireddy, S.R., Profitlich, T., Scherließ, R. and Urbanetz, N.A., Assessment of powder flowability in pharmaceutical tableting 10th World Congress of Chemical Engineering, Barcelona, Spain (2017) oral presentation

Renner, N., Steckel, H., Urbanetz, N.A., Scherließ, R., 2017. What could be learned from glass beads as model carrier system?, Drug Delivery to the Lungs 2017, Edinburgh, UK, pp. 250-25

Rhein, N., Birk, G., Girreser, U. and Scherließ, R., Stability of Formoterol as model for a reduction sensitive material in blends for inhalation, Drug Delivery to the Lungs 2017, Edinburgh, UK (2017)

Scherließ, R., Jüptner, A., Hellfritzsch, M., Kaj, C., Sarrailh, S., Vimont, A. and Williams, G., Spray dried formulations for pulmonary delivery – challenges in filling, aerosol generation and delivery, Drug Delivery to the Lungs 2017, Edinburgh, UK (2017)

Heidland, J. and Scherließ, R., Nano-in-microparticles for dry powder vaccination – possible for nasal application? , Drug Delivery to the Lungs 2017, Edinburgh, UK (2017) 396-399 (best academic poster)

Hertel, M., Schwarz, E., Kobler, M., Hauptstein, S., Steckel, H. and Scherließ, R., Influence of storage conditions on ternary dry powder inhaler formulations, Drug Delivery to the Lungs 2017, Edinburgh, UK (2017)

Saarinen, J., Gütter, F., Fraser, S., Isomäki, A., Antikainen, O., Scherließ, R., Peltonen, L., Santos, H.A. and Strachan, C.J., Visualisation of nanocrystal-cell interactions using coherent-anti Stokes Raman scattering (CARS) microscopy combined to multivariate data-analysis, Northern Pharma Network Meeting Helsinki, Finland (2016)

Saarinen, J., Gütter, F., Fraser, S., Isomäki, A., Antikainen, O., Scherließ, R., Peltonen, L., Santos, H.A. and Strachan, C.J., Multiplex coherent anti-Stokes Raman scattering (CARS) microscopy with multivariate data-analysis as a visualisation tool for probing un-labeled drug nanocrystals in cells, 27th Annual Symposium of the Finnish Society of Physical Pharmacy Helsinki, Finland (2016)

Saarinen, J., Gütter, F., Fraser, S., Isomäki, A., Antikainen, O., Scherließ, R., Peltonen, L., Santos, H.A. and Strachan, C.J., Visualisation of un-labeled drug nanocrystals in cells using coherent anti-Stokes Raman scattering (CARS) microscopy combined to multivariate data-analysis, Bridging Nordic Imaging and Cellular Imaging workshop, Gothenburg, Sweden (2016)

Heidland, J. and Scherließ, R., NiM powders for nasal vaccination – insights into particle forming process, World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, UK (2016)

Renner, N., Scherließ, R. and Steckel, H., Investigating the influence of carrier surface roughness on drug delivery by DPIs, World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, UK (2016)

Hertel, M., Scherließ, R., Schwarz, E., Littringer, E.M., Dogru, M., Hauptstein, S. and Steckel, H., Influence of fines on commercial lactose carriers and their dry powder inhalation performance, World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, UK (2016)

Hildebrandt, C., Scherließ, R., Gopireddy, S. and Urbanetz, N.A., Numerical analysis of die filling process within a lab scale pharmaceutical tableting machine, World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, UK (2016)

Arntz, P., Nassut, R., Steckel, H. and Scherließ, R., Pressurised bone void filler formulation, World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, UK (2016)

Rhein, N., Birk, G. and Scherließ, R., Influence of different inhalers on fine particle fraction of mannitol carriers in dry powder inhaler formulations, World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, UK (2016)

Mönckedieck, M., Scherließ, R., Kamplade, J., Walzel, P., Urbanetz, N.A. and Steckel, H., Spray dried mannitol carriers in inhalation – the influence of surface energy and API distribution on drug detachment, World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, UK (2016)

Saarinen, J., Gütter, F., Fraser, S., Isomäki, A., Antikainen, O., Scherließ, R., Peltonen, L., Santos, H.A. and Strachan, C.J., Multiplex coherent anti-Stokes Raman scattering (CARS) microscopy as a visualisation technique to probe drug nanocrystal–cell interactions, World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, UK (2016)

Gütter, F., Scherließ, R., Steckel, H., Saarinen, J., Strachan, C.J., Santos, H.A. and Peltonen, L., Production of nanocrystals and uptake studies in Caco-2 cells World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology Glasgow, UK (2016)

Wöll, S., Schiller, S. and Scherließ, R., Directional liposome functionalization using enzyme – mediated single-domain antibody conjugation, World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, UK (2016)

Renner, N., Scherließ, R. and Steckel, H., Glass beads as model carriers in dry powder inhalers:  Investigating the influence of surface coverage on inhalation performance, PARTEC, Nueremberg (2016)

Hildebrandt, C., Gopireddy, S.R., Scherließ, R. and Urbanetz, N.A., Simulation of powder flow within the force feeder of a pharmaceutical tablet press, PARTEC, Nueremberg (2016)

Albold, D. and Scherließ, R., Suitability of Microemulsions as Vehicle System for Dermal Protein Application, DPhG annual meeting, Munich, Germany (2016)

Hildebrandt, C., Gopireddy, S., Scherließ, R. and Urbanetz, N.A., Numerical analysis of powder flow in a lab-scale tableting machine, DPhG annual meeting, Munich, Germany (2016)

Wöll, S., Schiller, S. and Scherließ, R., Sortase-A mediates VHH – conjugation to differently PEGylated liposomes, DPhG annual meeting, Munich (2016)

Mönckedieck, M., Kamplade, J., Walzel, P., Steckel, H., Urbanetz, N.A. and Scherließ, R., Detachment of various spray dried drug particles from engineered mannitol carriers, Drug Delivery to the Lungs 27, Edinburgh, UK (2016) 146-149

Heidland, J. and Scherließ, R., Nano- in Microparticle powders for mucosal vaccination – understanding the particle forming process, Drug Delivery to the Lungs 27, Edinburgh, UK (2016) 110-113

Rhein, N., Birk, G. and Scherließ, R., Parteck M DPI – a novel mannitol as carrier in dry powder inhalation formulations, Drug Delivery to the Lungs 27, Edinburgh, UK (2016) 139-142

Renner, N., Steckel, H., Urbanetz, N.A. and Scherließ, R., A deeper insight into the impact of chemical surface properties on inhalation performance, Drug Delivery to the Lungs 27, Edinburgh, UK (2016) 316-319

Hertel, M., Schwarz, E., Littringer, E.M., Dogru, M., Hauptstein, S., Scherließ, R. and Steckel, H., The influence of the blender on the performance of ternary dry powder inhaler formulations, Drug Delivery to the Lungs 27, Edinburgh, UK (2016) 57-60

Albold, D., Scherließ, R., Proksch, E. and Steckel, H.A., Evaluation of Microneedle Devices for the Application of Dermal Protein Formulations, 4th Galenus Workshop "Drug Delivery to Human Skin", Saarbrücken (2015)

Hittinger, M., Mell, N., Janke, J., Huwer, H., Scherließ, R., Loretz, B., Schneider-Daum, N. and Lehr, C.-M., Autologous coculture of human alveolar cells for safety testing of airborne particles, Nano meets Future, Saarbrücken (2015)

Renner, N., Scherließ, R. and Steckel, H., Tailoring spray dried API particles of salbutamol sulphate and ipratropium bromide, 8th Polish German Symposium on Pharmaceutical Sciences, Kiel (2015)

Albold, D., Scherließ, R., Proksch, E. and Steckel, H., Evaluation of Microneedle Devices for the Application of Dermal Protein Formulations, 8th Polish German Symposium on Pharmaceutical Sciences, Kiel (2015)

Gütter, F., Scherließ, R. and Steckel, H., Stabilisers in nanocrystal production: Concentration dependency and cell toxicity, 8th Polish German Symposium on Pharmaceutical Sciences, Kiel (2015)

Heidland, J. and Scherließ, R., DC2.4 as an in-vitro test system for characterisation of promising formulations for nasal vaccination, 8th Polish German Symposium on Pharmaceutical Sciences, Kiel (2015)

Arntz, P., Scherließ, R. and Steckel, H., Optimisation of Calcium Phosphate Delivery from HFA-Suspensions, 8th Polish German Symposium on Pharmaceutical Sciences, Kiel, Germany (2015)

Mönckedieck, M., Kamplade, J., Fakner, P., Scherließ, R., Steckel, H. and Walzel, P., Impact of size and surface morphology of mannitol carrier particles on the FPF of DPI formulations, ISAM, Munich, Germany (2015)

Arntz, P., Nassut, R., Scherließ, R. and Steckel, H., Novel foamable cement formulation for application of antibiotics to bone voids, DPhG annual meeting, Düsseldorf, Germany (2015)

Hildebrandt, C., Gopireddy, S.R., Scherließ, R. and Urbanetz, N.A., Application of numerical simulations in pharmaceutical tableting, DPhG annual meeting, Düsseldorf (2015)

Albold, D. and Scherließ, R., Phospholipid-based microemulsions for the dermal application of proteins, 4th Symposium on Phospholipids in Pharmaceutical Research, Heidelberg, Germany (2015)

Wöll, S., Schiller, S. and Scherließ, R., Spray Drying of antigen – loaded DOTAP liposomes as powdered pulmonary vaccine, Symposium on Phospholipids in Pharmaceutical Research, Heidelberg, Germany (2015)

Saarinen, J., Gütter, F., Darville, N., Isomäki, A., Scherließ, R., Van den Mooter, G., Peltonen, L., Santos, H.A. and Strachan, C.J., Visualisation of itraconazole and glibenclamide nanocrystal cell uptake using coherent anti-Stokes Raman scattering (CARS) microscopy, FIP, Düsseldorf, Germany (2015)

Hertel, M., Schwarz, E., Littringer, E.M., Dogru, M., Scherließ, R. and Steckel, H., Influence of fines on commercial lactose carriers and their dry powder inhalation performance, Drug Delivery to the Lungs 26, Edinburgh, UK (2015)

Renner, N., Todorova, Z., Scherließ, R. and Steckel, H., Modified glass beads as model carriers to understand the performance of interactive powder blends, Drug Delivery to the Lungs 26, Edinburgh, UK (2015)

Mönckedieck, M., Kamplade, J., Walzel, P., Steckel, H. and Scherließ, R., Influence of mannitol carrier morphology on the DPI performance of different APIs, Drug Delivery to the Lungs 26, Edinburgh, UK (2015)

Rhein, N., Birk, G. and Scherließ, R., Characterisation of particle engineered Mannitol as alternative carriers in dry powder inhalation formulations, Drug Delivery to the Lungs 26, Edinburgh, UK (2015)

Mönckedieck, M., Scherließ, R., Steckel, H., 2014. Tailored salbutamol sulphate particles for dry powder inhalation by adjusting spray drying parameters, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbon

Diedrich, A. and Scherließ, R., Chitosan Nanoparticles for Pulmonary Protein Delivery, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbon (2014)

Janke, J. and Scherließ, R., Vaccination via the respiratory tract - porous PLGA-nanoparticles for a faster release, 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbon (2014)

Baleeiro, R.B., Rietscher, R., Diedrich, A., Scherließ, R., Hanefeld, A. and Walden, P., Cross-presentation of the tumor antigen Her2/neu involves neither the canonical nor the endosomal pathway – A novel MHC class I cross-presentation compartment in DCs, DC2014, Tours, France (2014)

Hanefeld, A., Schiller, S., Wolf, A., Weigandt, M., Scherließ, R., Diedrich, A., Janke, J., Knolle, P., Schröder, M., Walden, P., Baleerio, R., Lehr, C.M., Rietscher, R. and Schneider, M., Dendritic cell-targeting cancer vaccine formulations for pulmonary and peroral delivery, DPhG annual meeting, Frankfurt (2014)

Diedrich, A. and Scherließ, R., Stability of a Respirable Dry Powder Vaccine, DDL 25, Edinburgh, Scotland (2014)

Scherließ, R., Dennis, M., Carroll, M., Altrichter, J., Ajmera, A., Silman, N. et al., Protective immunization against H1N1 influenza A with spray-dried and electron-beam sterilized vaccines in non-human primates, 7th Vaccine and ISV Congress, Barcelona, Spain (2013) oral presentation

Janke, J. and Scherließ, R., Aerodynamic characterisation of PLGA nanoparticulate dry powder formulation for vaccine delivery via the respiratory tract, Proceedings of DDL 24, Edinburgh, Scotland (2013)

Buske, S. and Scherließ, R., Nasal deposition analysis of a nano-in-microparticle vaccine formulation in children and adults using cast models, Proceedings of DDL 24, Edinburgh, Scotland (2013)

Ajmera, A. and Scherließ, R., Dry Powder Formulation of Proteins via Spray Drying, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey (2012)

Buske, S. and Scherließ, R., Dispersion Behaviour of Dry Powder Nanoparticle-in-Microparticle Formulations for Nasal Vaccine Delivery, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey (2012)

Trows, S. and Scherließ, R., Stability of Antigen Loaded Dry Powder Microparticles for Nasal Vaccination, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turkey (2012)

Buske, S. and Scherließ, R., First steps in the development of a dry powder formulation for pulmonary vaccine delivery. Proceedings of DDL 23, Edinburgh, Scotland (2012) 353-356

Trows, S. and Scherließ, R., Release from antigen-loaded agarose nano-in-microparticles for nasal vaccination. Proceedings of DDL 23, Edinburgh, Scotland (2012) 333-336

Janke, J. and Scherließ, R., PLGA nanoparticles for vaccine delivery to the respiratory tract. Proceedings of DDL 23, Edinburgh, Scotland (2012) 357-360

Trows, S. and Scherließ, R., Development of a dry powder nasal vaccine formulation, 6th Polish-German Symposium, Düsseldorf, Germany (2011)

Buske, S. and Scherließ, R., Dry Powder Nanoparticulate Formulations for Mucosal Vaccination, ICMAT: NanoFormulation, Singapore (2011)

Scherließ, R., In vitro evaluation of dry powder nasal deposition from a single use nasal device, proceedings of DDL 22, Edinburgh, Scotland (2011) 189-192

Trows, S. and Westmeier, R., Development of a dry powder formulation for nasal vaccination, 7th World Congress of Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Valetta, Malta (2010)

Trows, S. and Scherließ, R., Development of a dry powder formulation for nasal vaccination, DPhG annual meeting, Braunschweig, Germany (2010)

Scherließ, R. and Trows, S., Novel Formulation Concept for Particulate Uptake of Vaccines via the Nasal Associated Lymphoid Tissue, Vaccine and ISV Annual Global Congress, Vienna, Austria (2010)

Scherließ, R., Comparison of in vitro methods to determine nasal versus lung deposition of a protein formulation, DDL 21, Edinburgh, Scotland (2010) 311-314, poster and oral presentation (Pat Burnell Award)

Westmeier, R., Rapid in-vitro screening test for respiratory toxicity, DDL20, Edinburgh, Scotland (2009) 20-23, oral presentation

Westmeier, R., Dubois, J., Lewis, N. and Steckel, H., Qualitative analysis of combination particles for pulmonal delivery, 6th World Meeting of Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology Barcelona, Spain (2008)

Westmeier, R. and Steckel, H., In-situ fine particle excipient as dispersion modifier for a dry powder inhalation product, proceedings of DDL 19, Edinburgh, Scotland (2008) 132-134

Westmeier, R. and Steckel, H., Aerodynamic assessment of salmeterol xinafoate and fluticasone propionate co-precipitates, proceedings of DDL 18, Edinburgh, Scotland (2007) 116-119

Westmeier, R. and Steckel, H., Enhanced dissolution of a new dry powder inhaler formulation, DPhG Joint Meeting, Erlangen, Germany (2007)

Westmeier, R. and Steckel, H., Dual particles containing Salmeterol xinafoate and Fluticasone propionate, proceedings of DDL 17, Edinburgh, Scotland (2006) 279-282