Publications

  1. Malik M, Eisend S, Kunze T, Einführung der Unit-Dose-Versorgung – Einfluss auf die Arzneimitteltherapiesicherheit im UKSH Kiel, Krankenhauspharmazie 2019;40:421–3040. Jahrgang Heft 9 September 2019.
  2. Häsler R, Kautz C, Rehman A, Podschun R, Gassling V, Brzoska P, Sherlock J, Gräsner JT, Hoppenstedt G, Schubert S, Ferlinz A, Lieb W, Laudes M, Heinsen FA, Scholz J, Harmsen D, Franke A, Eisend S, Kunze T, Fickenscher H, Ott S, Rosenstiel P, Schreiber S. The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany. Microbiome. 2018 Feb 20;6(1):37. doi: 10.1186/s40168-018-0414-7. PubMed PMID: 29458422; PubMed Central PMCID: PMC5819293.
  3. Gersonde F, Eisend S, Haake N, Kunze T. Physicochemical compatibility and emulsion stability of propofol with commonly used analgesics and sedatives in an intensive care unit. Eur J Hosp Pharm. 2017 Sep;24(5):293-303. doi: 10.1136/ejhpharm-2016-001038. Epub 2016 Sep 29. PubMed PMID: 31156960; PubMed Central PMCID: PMC6451515.
  4. Plitzko B, Havemeyer A, Kunze T, Clement B. The pivotal role of the mitochondrial amidoxime reducing component 2 in protecting human cells againstapoptotic effects of the base analog N6-hydroxylaminopurine. J Biol Chem. 2015 Apr 17;290(16):10126-35. doi: 10.1074/jbc.M115.640052. Epub 2015 Feb 23. PubMed PMID: 25713076; PubMed Central PMCID: PMC4400328.
  5. Knudsen L, Eisend S, Haake N, Kunze T, Physicochemical compatibility of commonly used analgesics and sedatives in the intensive care medicine, European Journal of Hospital Pharmacy: Science and Practice 2014, 21:161-166.
  6. Ott G, Plitzko B, Krischkowski C, Reichmann D, Bittner F, Mendel RR, Kunze T, Clement B, Havemeyer A. Reduction of sulfamethoxazole hydroxylamine (SMX-HA) by the mitochondrial amidoxime reducing component (mARC). Chem Res Toxicol. 2014 Oct 20;27(10):1687-95. doi: 10.1021/tx500174u. Epub 2014 Sep 18. PubMed PMID:25170804.
  7. Ott G, Reichmann D, Boerger C, Cascorbi I, Bittner F, Mendel RR, Kunze T, Clement B, Havemeyer A. Functional characterization of protein variants encoded by nonsynonymous single nucleotide polymorphisms in MARC1 and MARC2 in healthy Caucasians. Drug Metab Dispos. 2014 Apr;42(4):718-25. doi:10.1124/dmd.113.055202. Epub 2014 Jan 14. PubMed PMID: 24423752.
  8. Lühr I, Friedl A, Overath T, Tholey A, Kunze T, Hilpert F, Sebens S, Arnold N, Rösel F, Oberg HH, Maass N, Mundhenke C, Jonat W, Bauer M. Mammary fibroblasts regulate morphogenesis of normal and tumorigenic breast epithelial cells by mechanical and paracrine signals. Cancer Lett. 2012 Dec 28;325(2):175-88. doi:10.1016/j.canlet.2012.06.014. Epub 2012 Jul 7. PubMed PMID: 22776560; PubMed Central PMCID: PMC3708601.
  9. Blume L-F, Denker M, Gieseler F, Kunze T, Temperature corrected transepithelial electrical resistance (TEER)measurement to quantify rapid changes in paracellular permeability.Pharmazie. 2010 Jan;65(1):19-24. PubMed PMID:20187574
  10. Bürenheide A, Kunze T, Clement B, Inhibitory effects on cytochrome p450 enzymes of pentamidine and its amidoxime pro-drug. Basic Clin Pharmacol Toxicol. 103, 61-65, (2008).
  11. Gieseler F, Stelck B, Blume LF, Denker M, Dohrmann P, Mundhenke C, Bauerschlag D, Tiemann M, Kunze T., Coagulation and formation of malignant effusions. Hamostaseologie. 27, 273-277 (2007).
  12. Gieseler F, Lühr I, Kunze T, Mundhenke C, Maass N, Erhart T, Denker M, Beckmann D, Tiemann M, Schulte C, Dohrmann P, Cavaillé F, Godeau F, Gespach C., Activated coagulation factors in human malignant effusions and their contribution to cancer cell metastasis and therapy. Thromb Haemost. 97, 1023-1030 (2007).
  13. Havemeyer A, Bittner F, Wollers S, Mendel R, Kunze T, Clement B., Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme. J Biol Chem. 281, 34796-34802 (2006).
  14. Clement B, Kunze T, Heberling S., Reduction of N-omega-hydroxy-L-arginine to L-arginine by pig liver microsomes, mitochondria, and human liver microsomes. Biochem Biophys Res Commun. 349, 869-873 (2006).
  15. Zebothsen I, Kunze T, Clement B., Inhibitory effects of cytostatically active 6-aminobenzo[c]phenanthridines on cytochrome P450 enzymes in human hepatic microsomes. Basic Clin Pharmacol Toxicol. 99, 37-43 (2006).
  16. Xie WZ, Leibl M, Clark MR, Dohrmann P, Kunze T, Gieseler F., Activation of the coagulation system in cancerogenesis and metastasation. Biomed Pharmacother. 59, 70-75 (2005).
  17. T. Kunze and S. Heps, Phosphono analogues of glutathione: Inhibition of glutathione transferases, metabolic stability and uptake by cancer cells, Biochem. Pharmacol. 59, 973-981 (2000).
  18. T. Kunze, Purification and characterization of class Alpha and Mu glutathione S-transferase from porcine liver, Comp. Biochem. Physiol. 116B, 397-406 (1997).
  19. T. Kunze, Phosphono analogues of glutathione as new inhibitors of glutathione  S-transferases, Arch. Pharm. Pharm. Med. Chem. 329, 503-509 (1996).
  20. T. Kunze, Isolation and Biochemical characterization of the major cytosolic  glutathione S-transferases from porcine liver - comparision with the corresponding human enzymes, ISSX-Proceedings 7, 79 (1995).
  21. T. Kunze, Purification and biochemical characterization of the major cytosolic glutathione S-transferases from pig liver, Eur. J. Pharm. Sci. 2, 173 (1994).
  22. T. Kunze, Neue Glutathion-Analoga als Hemmstoffe von gereinigten Glutathion  S-Transferasen, Arch. Pharm. 326, 579 (1993).
  23. B. Clement and T. Kunze, The in vitro oxygenation of N,N'-diphenylguanidines,  Xenobiotica 23, 155-167 (1993).
  24. B. Clement and T. Kunze, Microsomal N-oxygenation of adenine to adenine 1-N- oxide, Arch. Pharm. 326, 25-27 (1993).
  25. B. Clement and T. Kunze, The reduction of 6-N-hydroxylaminopurine to adenine by xanthine oxidase, Biochem. Pharmacol. 44, 1501-1509 (1992).
  26. B. Clement und T. Kunze, Die Reduktion von 6-N-Hydroxyaminopurin durch  Xanthin Oxidase, Pharm. Unserer Zeit 20, 124 (1991).
  27. B. Clement, K. Lustig, H. Pfundner und T. Kunze, Untersuchungen von N- oxidativen Biotransformationsvorgängen mit gereinigten Enzymen, Arch. Pharm.  (Weinheim) 323, 663 (1990).
  28. B. Clement and T. Kunze, Hepatic microsomal N-hydroxylation of adenine to 6- N-hydroxylaminopurine, Biochem. Pharmacol. 39, 925-933 (1990).
  29. B. Clement und T. Kunze, Zur mikrosomalen N-Hydroxylierung des Adenins,  Arch. Pharm. 321, 601 (1988).